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Discordant courses of COVID‐19 in a cohabiting couple of lung transplant recipients
Author(s) -
DesmazesDufeu Nadine,
Coltey Bérengère,
Amari Lyria,
Gouitaa Marion,
Touzery Camille,
ReynaudGaubert Martine,
Chanez Pascal,
Cassir Nadim
Publication year - 2021
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13410
Subject(s) - medicine , immunosuppression , covid-19 , cystic fibrosis , pandemic , lung transplantation , lung , intensive care medicine , immunology , disease , infectious disease (medical specialty) , pathology , outbreak
COVID‐19 is a novel infectious disease caused by SARS‐CoV‐2 that emerged in late 2019 and which is now a pandemic. Solid organ transplant recipients are perceived to be at increased risk of severe COVID‐19 due to their chronic use of immunosuppressive drugs (ISDs) and to their associated conditions. Scarce data are available on the optimized management of ISDs in these patients and on its impact on presentation, clinical course, viral shedding, and outcome. We report here two cases of COVID‐19 in a cohabiting couple of lung transplant recipients for cystic fibrosis, who had different ISDs management and who developed discordant courses of their disease. Our findings suggest that the degree of their immunosuppression might be a reason for their different course and that ISDs might prove partially protective.