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Successful treatment with isavuconazole of subcutaneous phaeohyphomycosis in a kidney transplant recipient
Author(s) -
Dalla Gasperina Daniela,
Lombardi Domenico,
Rovelli Cristina,
Di Rosa Zaira,
Lepera Valentina,
Baj Andreina,
Nava Alice,
Lombardi Gianluigi,
Grossi Paolo Antonio
Publication year - 2019
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13197
Subject(s) - phaeohyphomycosis , medicine , alternaria alternata , alternaria , incidence (geometry) , dermatology , kidney transplantation , antifungal , pathology , transplantation , biology , botany , physics , optics , genetics
Abstract Phaeohyphomycosis is a diverse group of uncommon mycotic infections caused by dematiaceous fungi which appears to be increasing in incidence, particularly in transplant recipients. Alternaria is the most frequent isolated genus. Subcutaneous, pulmonary and disseminated disease are the most common sites of Alternaria infection in solid organ transplant recipients. We report the first case, to our knowledge, of a kidney transplant recipient with Alternaria alternata subcutaneous infection who was successfully treated with isavuconazole.