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Successful re‐transplantation in patient with recurrent parvovirus B19 pure red cell aplasia
Author(s) -
Inamdar Neeraj,
Nada Ritambhra,
Minz Ranjana,
Kenwar Deepesh Benjamin,
Singh Sarabpreet,
Sharma Ashish,
Kumar Vivek,
Rathi Manish,
Kohli Harbir S.,
Ramachandran Raja
Publication year - 2019
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13164
Subject(s) - medicine , parvovirus , immunosuppression , transplantation , immunology , pure red cell aplasia , antibody , kidney transplantation , immunity , virus , immune system , bone marrow
Impaired cell‐mediated, as well as antibody‐mediated immunity predisposes a renal transplant recipient to a wide variety of atypical infection. With an increasing number of re‐transplant, the balance between immunosuppression and the risk of recurrent disease poses a clinical and therapeutic challenge. Here, we report a successful re‐transplantation in a case of parvovirus B19 infection leading to anaemia and collapsing glomerulopathy in the allograft managed with intravenous immunoglobulin (IVIG) and reduction of immunosuppression. This case emphasizes re‐consideration to renal transplant after clearance of the virus in a previous renal allograft lost to PVB19 infection.