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An unusual case of Kaposi sarcoma masquerading as cystitis in a kidney transplant recipient
Author(s) -
Nair Vinay,
Sheikh Fatima,
Hirschwerk David,
Fahmy Ahmed,
Bhaskaran Madhu,
Grodstein Elliot,
Winnick Aaron,
Maki Robert,
Teperman Lewis,
Molmenti Ernesto
Publication year - 2019
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13132
Subject(s) - medicine , dysuria , sarcoma , differential diagnosis , pathology , malignancy , organ transplantation , gastrointestinal tract , urinary system , lymph , dermatology , transplantation , surgery
Abstract Human Herpes Virus‐8 (HHV‐8) may reactivate in immunocompromised patients including recipients of solid organ transplants. Reactivation of HHV‐8 may result in Kaposi sarcoma (KS). KS typically occurs with dermatologic involvement but can affect virtually any other organ; most commonly the gastrointestinal tract. We present a diagnostically challenging case of KS in a South American woman 7 months after kidney transplant. She presented with recurrent urinary tract infection manifested by pelvic pain and dysuria. Imaging studies revealed bladder thickening with pelvic lymphadenopathy. Findings on tissue biopsied from the bladder and lymph nodes were consistent with KS. Her skin was not affected. This case illustrates that KS and other HHV‐8–related diseases should be on the differential diagnosis as a cause of mass lesions as well as lymphadenopathy in transplant recipients. The case exemplifies the need to pursue a tissue diagnosis in immunocompromised patients when a diagnosis is uncertain.