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Lymphocytic choriomeningitis virus meningoencephalitis in a renal transplant recipient following exposure to mice
Author(s) -
Tanveer Farah,
Younas Mariam,
Fishbain Joel
Publication year - 2018
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13013
Subject(s) - lymphocytic choriomeningitis , meningoencephalitis , medicine , renal transplant , immunology , hydrocephalus , immunity , virus , virology , immune system , transplantation , surgery , cd8
Solid organ transplant recipients (SOTR) are at increased risk for a wide variety of typical and atypical infections as a consequence of impaired cell mediated and humoral immunity. We report a case of meningoencephalitis in a renal transplant recipient caused by lymphocytic choriomeningitis virus (LCMV) acquired by exposure to mice excreta. The clinical course was complicated by the development of hydrocephalus, requiring a ventriculoperitoneal shunt. To our knowledge, this is the first reported case of LCMV infection in a SOTR that was not organ donor derived.