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Severe hematuria in a hematopoietic cell transplant recipient caused by Ureaplasma urealyticum not by BK virus or adenovirus infection
Author(s) -
Choi GwangJun,
Kim SunJa,
Kang JiMan,
Choi Sae Rom,
Yoo Keon Hee,
Kim YaeJean
Publication year - 2018
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12921
Subject(s) - ureaplasma urealyticum , medicine , hematopoietic cell , bk virus , immunology , haematopoiesis , virology , virus , transplantation , stem cell , microbiology and biotechnology , mycoplasma , kidney transplantation , biology , genetics
A 17‐year‐old male with acute lymphoblastic leukemia developed severe hematuria and scrotal swelling after haploidentical hematopoietic cell transplantation (HCT). Urine culture was negative. BK virus and adenovirus were negative. However, Ureaplasma urealyticum was detected. He showed dramatic improvement after doxycycline treatment. This is the first report in the literature of hemorrhagic cystitis caused by U. urealyticum in a HCT recipient. In HCT recipients with hemorrhagic cystitis, U. urealyticum should be considered as a potential cause.