Premium
Cutaneous ulcerations caused by Paecilomyces variotii in a renal transplant recipient
Author(s) -
Eren Davut,
Eroglu Eray,
Ulu Kilic Aysegul,
Atalay Mustafa Altay,
Mumcu Necati,
Sipahioglu Murat Hayri,
Canoz Ozlem,
Koc Ayse Nedret,
Oymak Oktay
Publication year - 2018
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12871
Subject(s) - medicine , paecilomyces , voriconazole , cellulitis , skin biopsy , dermatology , transplantation , biopsy , kidney transplantation , antifungal , pathology , surgery , botany , biology
Skin infections caused by Paecilomyces species have been rarely described in patients with solid organ transplantation. Cutaneous manifestations are highly variable and include erythematous macules, nodules, pustules, and vesicular and necrotic lesions. The diagnosis of these infections is generally made by examination of a skin biopsy. Management of these fungal infections is difficult due to the immunocompromised state of the patients. Moreover, antifungal therapy and immunosuppressive drug interactions should be considered during treatment management. Herein, we reported a case of cellulitis caused by Paecilomyces variotii in a 56‐year‐old man who had undergone a kidney transplantation. Erythematous macular and nodular lesions on the left hand and left foot appeared first; within 2 months the skin lesions became ulcerated, hemorrhagic, and progressively painful and the patient was admitted to our hospital. The diagnosis was made by skin biopsy and tissue culture. The skin lesions resolved by the sixth week of the treatment with voriconazole.