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A rare case of Epstein‐Barr virus‐associated hepatosplenic smooth muscle tumors after kidney transplantation
Author(s) -
Pircher C.,
Schneeberger S.,
Boesmueller C.,
Agaimy A.,
Zoller H.,
Bale R.,
Henninger B.,
Mayer G.,
Neuwirt H.
Publication year - 2018
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12860
Subject(s) - medicine , immunosuppression , sirolimus , tacrolimus , radiofrequency ablation , transplantation , kidney transplantation , kidney , virus , liver transplantation , epstein–barr virus , spleen , pathology , surgery , ablation , immunology
A 27‐year old caucasian male was diagnosed 2.7 years after kidney transplantation with Epstein‐Barr virus ( EBV )‐associated smooth muscle tumors in liver and spleen. The reduction in immunosuppression and conversion from tacrolimus to sirolimus did not lead to a regression of the tumors. Additionally, the patient developed a cellular rejection of his renal allograft, which was successfully treated. A combined approach with stereotactic radiofrequency ablation ( SRFA ) and surgical resection was effective in the treatment of the tumors.