Premium
Treatment of human polyomavirus‐7‐associated rash and pruritus with topical cidofovir in a lung transplant patient: Case report and literature review
Author(s) -
Smith Shane D. B.,
Erdag Gulsun,
Cuda Jonathan D.,
Rangwala Sophie,
Girardi Nicholas,
Bibee Kristin,
Orens Jonathan B.,
Prono Maria Dioverti,
Toptan Tuna,
Loss Manisha J.
Publication year - 2018
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12793
Subject(s) - cidofovir , medicine , rash , dermatology , adverse effect , lung , regimen , surgery , immunology , virus
Human polyomavirus‐7‐associated rash and pruritus ( PVARP ) is a chronic superficial viral skin infection, which primarily impacts immunocompromised individuals. We report on a case of PVARP in a lung transplant recipient. Our patient developed symptoms 13 years after being on his immunosuppressive regimen, with an insidious course of progressive gray lichenification with marked islands of sparing and quality of life‐altering pruritus. Treatment for PVARP is not established; however, topical cidofovir combined with immunomodulation may offer sustained therapeutic benefit.