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A cluster of scedosporiosis in lung transplant candidates and recipients: The Zurich experience and review of the literature
Author(s) -
Abela Irene A.,
Murer Christian,
Schuurmans Macé M.,
Schmitt Juergen W.,
Muller Frabci,
Imkamp Frank,
Mueller Nicolas J.,
Benden Christian
Publication year - 2018
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12792
Subject(s) - medicine , cystic fibrosis , context (archaeology) , lung transplantation , intensive care medicine , transplantation , immunology , paleontology , biology
Abstract S cedosporium species are fungal pathogens increasingly recognized in cystic fibrosis ( CF ). They can cause multiresistant, life‐threatening infections that are of particular concern in CF patients undergoing lung transplantation, as optimal treatment remains unclear. Here, we describe our Zurich experience of CF patients with S cedosporium infection. Disseminated infection occurred in one patient after transplantation and was successfully treated. We propose a step‐by‐step approach to treat candidates with colonization, and discuss our cases in the context of the current literature.