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Prolonged viremia in dengue virus infection in hematopoietic stem cell transplant recipients and patients with hematological malignancies
Author(s) -
Souza Pereira Bárbara Brito,
Darrigo Junior Luiz Guilherme,
Mello Costa Thalita Cristina,
Felix Alvina Clara,
Simoes Belinda P.,
Stracieri Ana Beatriz,
Silva Paula Moreira,
Mauad Marcos,
Machado Clarisse M.
Publication year - 2017
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12721
Subject(s) - dengue fever , viremia , medicine , rash , dengue virus , hematopoietic stem cell transplantation , immunology , disease , hematopoietic stem cell , stem cell , virology , virus , haematopoiesis , biology , genetics
Fever, skin rash, headache, and thrombocytopenia are considered hallmarks of dengue infection. However, these symptoms are frequently observed in infectious and non‐infectious complications of hematopoietic stem cell transplant recipients and oncohematological patients. Thus, laboratory confirmation of dengue is relevant for prompt intervention and proper management of dengue in endemic and non‐endemic regions. Because no prospective study of dengue has been conducted in these populations, the actual morbidity and mortality of dengue is unknown. In the present series, we describe five cases of dengue in patients living in endemic areas, emphasizing the prolonged course of the disease and the occurrence of prolonged viremia.