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JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature
Author(s) -
Yang Doyle,
Keys Brandon,
J. Conti David,
Foulke Llewellyn,
Stellrecht Kathleen,
Cook Linda,
LopezSoler Reynold I.
Publication year - 2017
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12654
Subject(s) - medicine , nephropathy , renal transplant , rare disease , polyomavirus infections , bk virus , transplantation , kidney transplantation , disease , pathology , immunology , diabetes mellitus , endocrinology
JC polyomavirus‐associated nephropathy ( JC ‐ PVAN ) is a rare but challenging cause of renal dysfunction. We report JC ‐ PVAN in a renal allograft recipient and highlight the obstacles in definitive diagnosis of this disease entity. A deceased‐donor renal transplant recipient was diagnosed with JC polyomavirus nephritis 4 years after transplantation. Immunosuppressive agents were subsequently reduced, resulting in an initial stabilization of renal function. We present this interesting case and discuss the challenges with diagnosing and treating this rare entity.