S trongyloides  hyperinfection following hematopoietic stem cell transplant in a patient with  HTLV ‐1‐associated T‐cell leukemia | Zendy

Alpern Jonathan D. | Zendy; Arbefeville Sophie S. | Zendy; Vercellotti Gregory | Zendy; Ferrieri Patricia | Zendy; Green Jaime S. | Zendy

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S trongyloides hyperinfection following hematopoietic stem cell transplant in a patient with HTLV ‐1‐associated T‐cell leukemia

Author(s) -

Alpern Jonathan D.,

Arbefeville Sophie S.,

Vercellotti Gregory,

Ferrieri Patricia,

Green Jaime S.

Publication year - 2017

Publication title -

transplant infectious disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.69

H-Index - 67

eISSN - 1399-3062

pISSN - 1398-2273

DOI - 10.1111/tid.12638

Subject(s) - strongyloides stercoralis , strongyloidiasis , strongyloides , medicine , immunosuppression , neutropenia , immunology , leukemia , hematopoietic stem cell transplantation , haematopoiesis , stem cell , transplantation , biology , helminths , chemotherapy , genetics

S trongyloides stercoralis has the potential to cause accelerated autoinfection in immunocompromised hosts. Screening tests for strongyloidiasis may be falsely negative in the setting of immunosuppression. We report a case of S trongyloides hyperinfection syndrome in a patient with human T‐lymphotropic virus type 1‐associated T‐cell leukemia early after hematopoietic stem cell transplant. The diagnosis was made by stool ova and parasite examination, despite a negative screening enzyme‐linked immunosorbent assay. Because of anticipated prolonged neutropenia, an extended course of treatment was utilized.

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