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S trongyloides hyperinfection following hematopoietic stem cell transplant in a patient with HTLV ‐1‐associated T‐cell leukemia
Author(s) -
Alpern Jonathan D.,
Arbefeville Sophie S.,
Vercellotti Gregory,
Ferrieri Patricia,
Green Jaime S.
Publication year - 2017
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12638
Subject(s) - strongyloides stercoralis , strongyloidiasis , strongyloides , medicine , immunosuppression , neutropenia , immunology , leukemia , hematopoietic stem cell transplantation , haematopoiesis , stem cell , transplantation , biology , helminths , chemotherapy , genetics
S trongyloides stercoralis has the potential to cause accelerated autoinfection in immunocompromised hosts. Screening tests for strongyloidiasis may be falsely negative in the setting of immunosuppression. We report a case of S trongyloides hyperinfection syndrome in a patient with human T‐lymphotropic virus type 1‐associated T‐cell leukemia early after hematopoietic stem cell transplant. The diagnosis was made by stool ova and parasite examination, despite a negative screening enzyme‐linked immunosorbent assay. Because of anticipated prolonged neutropenia, an extended course of treatment was utilized.