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Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation
Author(s) -
Yamada Yuji,
Osumi Tomoo,
Imadome KenIchi,
Takahashi Etsuko,
Ohye Tamae,
Yoshikawa Tetsushi,
Tomizawa Daisuke,
Kato Motohiro,
Matsumoto Kimikazu
Publication year - 2017
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12636
Subject(s) - medicine , cord blood , transmission (telecommunications) , transplantation , virology , human herpesvirus 6 , human blood , immunology , virus , herpesviridae , viral disease , surgery , telecommunications , physiology , computer science
Chromosomally integrated human herpesvirus 6 (ci HHV ‐6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ci HHV ‐6 via cord blood transplantation. Distinguishing transmission of ci HHV ‐6 from HHV ‐6 reactivation in cases with high titer of HHV ‐6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.