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Evidence of hepatitis E virus transmission by renal graft
Author(s) -
Pourbaix Annabelle,
Ouali Nacera,
Soussan Patrick,
Roque Afonso Anne Marie,
Péraldi MarieNoelle,
Rondeau Eric,
Peltier Julie
Publication year - 2017
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12624
Subject(s) - medicine , hepatitis e virus , transmission (telecommunications) , virology , cirrhosis , serology , virus , polymerase chain reaction , hepatitis , immunology , antibody , genotype , biology , gene , biochemistry , electrical engineering , engineering
Hepatitis E virus ( HEV ) can cause chronic infection among immunocompromised patients, especially solid organ transplant recipients, and can evolve to cirrhosis. Several modes of transmission are known. Here we describe the first two cases, to our knowledge, of HEV infection transmitted by a kidney graft from the same infected donor that led to chronic hepatitis. Consequently, systematic screening of donors by HEV serology and HEV RNA detection by polymerase chain reaction, particularly in endemic regions, should be considered.