Donor‐derived tuberculosis ( TB ): isoniazid‐resistant  TB  transmitted from a lung transplant donor with inadequately treated latent infection | Zendy

Jensen T.O. | Zendy; Darley D.R. | Zendy; Goeman E.E. | Zendy; Shaw K. | Zendy; Marriott D.J. | Zendy; Glanville A.R. | Zendy

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Donor‐derived tuberculosis ( TB ): isoniazid‐resistant TB transmitted from a lung transplant donor with inadequately treated latent infection

Author(s) -

Jensen T.O.,

Darley D.R.,

Goeman E.E.,

Shaw K.,

Marriott D.J.,

Glanville A.R.

Publication year - 2016

Publication title -

transplant infectious disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.69

H-Index - 67

eISSN - 1399-3062

pISSN - 1398-2273

DOI - 10.1111/tid.12580

Subject(s) - medicine , isoniazid , latent tuberculosis , tuberculosis , lung , pulmonary tuberculosis , complication , immunology , mycobacterium tuberculosis , surgery , pathology

Donor‐derived tuberculosis ( TB ) is an increasingly recognized complication of solid organ transplantation. We report a case of isoniazid‐resistant pulmonary TB in a lung transplant recipient. The patient acquired the infection from the lung donor who was previously empirically treated with isoniazid for latent TB . The case highlights the caveat that, while adequate treatment of latent TB with isoniazid is presumed, meticulous screening of donors is required.

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