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Donor‐derived tuberculosis ( TB ): isoniazid‐resistant TB transmitted from a lung transplant donor with inadequately treated latent infection
Author(s) -
Jensen T.O.,
Darley D.R.,
Goeman E.E.,
Shaw K.,
Marriott D.J.,
Glanville A.R.
Publication year - 2016
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12580
Subject(s) - medicine , isoniazid , latent tuberculosis , tuberculosis , lung , pulmonary tuberculosis , complication , immunology , mycobacterium tuberculosis , surgery , pathology
Donor‐derived tuberculosis ( TB ) is an increasingly recognized complication of solid organ transplantation. We report a case of isoniazid‐resistant pulmonary TB in a lung transplant recipient. The patient acquired the infection from the lung donor who was previously empirically treated with isoniazid for latent TB . The case highlights the caveat that, while adequate treatment of latent TB with isoniazid is presumed, meticulous screening of donors is required.