Disseminated   H ormographiella aspergillata  infection with involvement of the lung, brain, and small intestine following allogeneic hematopoietic stem cell transplantation: case report and literature review | Zendy

Nanno S. | Zendy; Nakane T. | Zendy; Okamura H. | Zendy; Nishimoto M. | Zendy; Koh H. | Zendy; Nakamae H. | Zendy; Ohsawa M. | Zendy; Yarita K. | Zendy; Kamei K. | Zendy; Hino M. | Zendy

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Disseminated H ormographiella aspergillata infection with involvement of the lung, brain, and small intestine following allogeneic hematopoietic stem cell transplantation: case report and literature review

Author(s) -

Nanno S.,

Nakane T.,

Okamura H.,

Nishimoto M.,

Koh H.,

Nakamae H.,

Ohsawa M.,

Yarita K.,

Kamei K.,

Hino M.

Publication year - 2016

Publication title -

transplant infectious disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.69

H-Index - 67

eISSN - 1399-3062

pISSN - 1398-2273

DOI - 10.1111/tid.12561

Subject(s) - medicine , lung , hematopoietic stem cell transplantation , stem cell , hematopoietic cell , transplantation , haematopoiesis , pathology , immunology , intensive care medicine , biology , genetics

Disseminated infection by H ormographiella aspergillata is extremely rare and small intestine involvement has not been reported previously. A 51‐year‐old man with myelodysplastic syndrome developed pneumonia after cord blood cell transplantation. Fungal growth from the biopsied lung was identified as H . aspergillata by morphology and the gene analysis. Although antifungal agents including voriconazole and liposomal amphotericin B were administered, he died of disseminated H . aspergillata infection. We review the literature and discuss the treatment and prognosis.

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