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Disseminated H ormographiella aspergillata infection with involvement of the lung, brain, and small intestine following allogeneic hematopoietic stem cell transplantation: case report and literature review
Author(s) -
Nanno S.,
Nakane T.,
Okamura H.,
Nishimoto M.,
Koh H.,
Nakamae H.,
Ohsawa M.,
Yarita K.,
Kamei K.,
Hino M.
Publication year - 2016
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12561
Subject(s) - medicine , lung , hematopoietic stem cell transplantation , stem cell , hematopoietic cell , transplantation , haematopoiesis , pathology , immunology , intensive care medicine , biology , genetics
Disseminated infection by H ormographiella aspergillata is extremely rare and small intestine involvement has not been reported previously. A 51‐year‐old man with myelodysplastic syndrome developed pneumonia after cord blood cell transplantation. Fungal growth from the biopsied lung was identified as H . aspergillata by morphology and the gene analysis. Although antifungal agents including voriconazole and liposomal amphotericin B were administered, he died of disseminated H . aspergillata infection. We review the literature and discuss the treatment and prognosis.