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Early onset of nontuberculous mycobacterial pulmonary disease contributes to the lethal outcome in lung transplant recipients: report of two cases and review of the literature
Author(s) -
Jankovic Makek M.,
Pavlisa G.,
Jakopovic M.,
Redzepi G.,
Zmak L.,
Vukic Dugac A.,
Hecimovic A.,
Mazuranic I.,
Jaksch P.,
Klepetko W.,
Samarzija M.
Publication year - 2016
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12481
Subject(s) - medicine , nontuberculous mycobacteria , lung transplantation , disease , lung disease , population , transplantation , lung , intensive care medicine , immunology , pathology , tuberculosis , mycobacterium , environmental health
Lung transplant (LuTx) recipients represent a population at risk of nontuberculous mycobacterial pulmonary disease ( NTM ‐ PD ). Yet the risk factors, the timing of NTM ‐ PD after transplantation, and the association with allograft dysfunction all remain poorly defined. We report 2 cases of early‐onset NTM ‐ PD and review the literature, focusing on NTM ‐ PD in LuTx recipients not colonized with NTM prior to transplantation. In addition, we summarize the main characteristics and differences between early‐ and late‐onset disease.