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Successful treatment of hepatitis E virus‐associated cryoglobulinemic membranoproliferative glomerulonephritis with ribavirin
Author(s) -
Del Bello A.,
GuilbeauFrugier C.,
Josse A.G.,
Rostaing L.,
Izopet J.,
Kamar N.
Publication year - 2015
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12353
Subject(s) - membranoproliferative glomerulonephritis , medicine , ribavirin , immunology , hepatitis c , hepatitis c virus , cryoglobulinemia , glomerulonephritis , virus , kidney , virology
Abstract Hepatitis E virus genotype‐3 ( HEV 3) infection can cause chronic hepatitis in immunosuppressed patients and induce extra‐hepatic manifestations, such as neurological symptoms, kidney injuries, and immune‐mediated thrombocytopenia. Very few cases of HEV ‐induced kidney manifestations have been reported. Herein, we report, for the first time, a case of de novo membranoproliferative glomerulonephritis that occurred in a kidney transplant patient who developed a chronic HEV 3 infection, which was successfully treated with ribavirin.