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Fulminant endocarditis and disseminated infection caused by carbapenem‐resistant A cinetobacter baumannii in a renal‐pancreas transplant recipient
Author(s) -
Patel G.,
Perez F.,
Hujer A.M.,
Rudin S.D.,
Augustine J.J.,
Jacobs G.H.,
Jacobs M.R.,
Bonomo R.A.
Publication year - 2015
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12351
Subject(s) - medicine , fulminant , acinetobacter baumannii , endocarditis , carbapenem , renal transplant , microbiology and biotechnology , antibiotics , pseudomonas aeruginosa , transplantation , bacteria , biology , genetics
A cinetobacter baumannii is an important cause of healthcare‐associated infections, and is particularly problematic among patients who undergo organ transplantation. We describe a case of fulminant sepsis caused by carbapenem‐resistant A . baumannii harboring the bla OXA‐23 carbapenemase gene and belonging to international clone II. This isolate led to the death of a patient 6 days after simultaneous kidney‐pancreas transplantation. Autopsy findings revealed acute mitral valve endocarditis, myocarditis, splenic and renal emboli, peritonitis, and pneumonia. This case highlights the severe nature of certain A . baumannii infections and the vulnerability of transplanted patients to the increasingly intractable “high‐risk” clones of multidrug‐resistant organisms.