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Prolonged respiratory viral shedding in transplant patients
Author(s) -
Lima C.R.A.,
Mirandolli T.B.,
Carneiro L.C.,
Tusset C.,
Romer C.M.,
Andreolla H.F.,
Baethgen L.F.,
Pasqualotto A.C.
Publication year - 2014
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12167
Subject(s) - viral shedding , medicine , respiratory system , rhinovirus , virus , viral load , virology , clinical significance , immunology , cohort
Respiratory viral infections are frequent causes of morbidity in transplant patients. We screened symptomatic adult transplant recipients for respiratory viruses in a cohort of patients attending a referral medical center in B razil. The duration of viral shedding and the prevalence of viral codetections were also determined. During a 1‐year period (2011–2012), swabs were obtained from 50 patients. An in‐house polymerase chain reaction panel designed to detect 10 viruses was used. Viruses were identified in 19 (38%) patients, particularly parainfluenza III (32%) and the respiratory syncytial virus (20%); multiple viruses were identified in 26% of patients. Prolonged viral shedding was observed with 60% of individuals excreting viruses for >10 days. The clinical and epidemiologic relevance of prolonged viral shedding remains to be determined.