Premium
Disseminated R hizopus microsporus infection following allogeneic hematopoietic stem cell transplantation in a child with severe aplastic anemia
Author(s) -
Ye B.,
Yu D.,
Zhang X.,
Shao K.,
Chen D.,
Wu D.,
Zhang Y.,
Zhou Y.,
Shen Y.,
Yu Q.
Publication year - 2013
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12144
Subject(s) - medicine , hematopoietic stem cell transplantation , aplastic anemia , transplantation , stem cell , amphotericin b , immunology , antifungal , bone marrow , biology , dermatology , genetics
Disseminated R hizopus microsporus infections are uncommon in children and are resistant to echinocandin and azole antifungal agents. We describe a child with severe aplastic anemia who developed disseminated R . microsporus infection following allogeneic hematopoietic stem cell transplantation. R . microsporus was identified microscopically in the hepatic drain culture and was confirmed on the basis of 18S r RNA and 28S r RNA sequence analyses. The patient was treated successfully with hepatic drainage and amphotericin B deoxycholate.