Disseminated   R hizopus microsporus  infection following allogeneic hematopoietic stem cell transplantation in a child with severe aplastic anemia | Zendy

Ye B. | Zendy; Yu D. | Zendy; Zhang X. | Zendy; Shao K. | Zendy; Chen D. | Zendy; Wu D. | Zendy; Zhang Y. | Zendy; Zhou Y. | Zendy; Shen Y. | Zendy; Yu Q. | Zendy

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Disseminated R hizopus microsporus infection following allogeneic hematopoietic stem cell transplantation in a child with severe aplastic anemia

Author(s) -

Ye B.,

Yu D.,

Zhang X.,

Shao K.,

Chen D.,

Wu D.,

Zhang Y.,

Zhou Y.,

Shen Y.,

Yu Q.

Publication year - 2013

Publication title -

transplant infectious disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.69

H-Index - 67

eISSN - 1399-3062

pISSN - 1398-2273

DOI - 10.1111/tid.12144

Subject(s) - medicine , hematopoietic stem cell transplantation , aplastic anemia , transplantation , stem cell , amphotericin b , immunology , antifungal , bone marrow , biology , dermatology , genetics

Disseminated R hizopus microsporus infections are uncommon in children and are resistant to echinocandin and azole antifungal agents. We describe a child with severe aplastic anemia who developed disseminated R . microsporus infection following allogeneic hematopoietic stem cell transplantation. R . microsporus was identified microscopically in the hepatic drain culture and was confirmed on the basis of 18S r RNA and 28S r RNA sequence analyses. The patient was treated successfully with hepatic drainage and amphotericin B deoxycholate.

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