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Cryptococcal meningitis presenting as sinusitis in a renal transplant recipient
Author(s) -
Iyer S.P.,
Movva K.,
Wiebel M.,
Chandrasekar P.,
Alangaden G.,
Carron M.,
Tranchida P.,
Revankar S.G.
Publication year - 2013
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12128
Subject(s) - medicine , meningitis , sinusitis , renal transplant , cryptococcal meningitis , immunology , kidney , surgery , human immunodeficiency virus (hiv) , viral disease
Cryptococcal meningitis is a relatively common invasive fungal infection in immunocompromised patients, especially in solid organ transplant recipients. Clinical presentation typically includes fever, headache, photophobia, neck stiffness, and/or altered mental status. Unusual presentations may delay diagnosis. Therapy is challenging in renal transplant patients because of the nephrotoxicity associated with amphotericin B, the recommended treatment. We present a case of cryptococcal meningitis in a renal transplant recipient presenting as acute sinusitis with successful treatment using fluconazole as primary therapy.