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A messenger at the door: cytomegalovirus retinitis in myeloma patients with progressive disease
Author(s) -
Teh B.W.,
Khot A.S.,
Harrison S.J.,
Prince H.M.,
Slavin M.A.
Publication year - 2013
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12106
Subject(s) - medicine , retinitis , cytomegalovirus retinitis , immunosuppression , cytomegalovirus , multiple myeloma , immunology , disease , population , human cytomegalovirus , herpesviridae , viral disease , human immunodeficiency virus (hiv) , virus , environmental health
Cytomegalovirus ( CMV ) retinitis is an uncommon manifestation of CMV disease and is a marker of severe and profound immunosuppression in human immunodeficiency virus‐positive patients. Here, we describe 2 cases of CMV retinitis in myeloma patients with progressive disease, following autologous stem cell transplantation and immunomodulatory therapy for myeloma. To our knowledge, this is the first report of CMV retinitis in this patient population. This report illustrates the need for close monitoring of relapsed and refractory myeloma patients for new presentations of opportunistic infections secondary to severe immunosuppression.