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Fumagillin‐induced aseptic meningoencephalitis in a kidney transplant recipient with microsporidiosis
Author(s) -
Audemard A.,
Le Bellec M.L.,
Carluer L.,
Dargère S.,
Verdon R.,
Castrale C.,
Lobbedez T.,
Hurault de Ligny B.
Publication year - 2012
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12010
Subject(s) - microsporidiosis , fumagillin , medicine , meningoencephalitis , immunosuppression , opportunistic infection , microsporidia , enterocytozoon bieneusi , immunology , virology , human immunodeficiency virus (hiv) , viral disease , biology , microbiology and biotechnology , angiogenesis , protozoal disease , malaria , spore
Microsporidiosis is an opportunistic infection in organ transplant recipients and patients with other cellular immunodeficiency. Fumagillin is an effective treatment against E nterocytozoon bieneusi , one of the two main species causing the microsporidiosis involved in human diseases. We report the first case, to our knowledge, of a probable drug‐induced aseptic meningoencephalitis, after administration of fumagillin in a kidney transplant recipient with microsporidiosis.