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Persistent R hodococcus equi infection in a renal transplant patient: case report and review of the literature
Author(s) -
Me V.,
Gottlieb T.,
Gallagher M.,
Cheong E.L.
Publication year - 2012
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.12008
Subject(s) - medicine , immunosuppression , rhodococcus equi , renal transplant , pneumonia , antibiotics , intensive care medicine , epidemiology , disease , surgery , transplantation , virulence , microbiology and biotechnology , biochemistry , chemistry , biology , gene
R hodococcus equi is a pathogen that mainly causes infection in immunocompromised hosts. We report a case of relapsing R . equi pulmonary infection in a 57‐year‐old male renal transplant recipient who was treated with 12 months of antibiotics, adjunctive surgery, and a reduction in his immunosuppression. He suffered from relapsing disease, treatment‐related complications, and ultimately died of P neumocystis pneumonia. Case reports in the literature portray a good cure rate for transplant‐related R . equi infections, with shorter durations of antibiotics. The case illustrates the difficulties in the management of R . equi infections. Forty cases from the literature were reviewed and compared in terms of epidemiology, location of infection, transplant type, immunosuppression used, treatment used, outcomes, and possible exposures.