Open AccessImpact of neoadjuvant and adjuvant chemotherapy on invasive lobular carcinoma: A propensity score‐matched analysis of SEER data
Author(s) -
Watanuki Rurina,
Hayashida Tetsu,
Yokoe Takamichi,
Kawai Yuko,
Kikuchi Masayuki,
Nakashoji Ayako,
Nagayama Aiko,
Seki Tomoko,
Takahashi Maiko,
Kitagawa Yuko
Publication year - 2020
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/tbj.13884
Subject(s) - medicine , propensity score matching , perioperative , chemotherapy , oncology , retrospective cohort study , neoadjuvant therapy , surgery , cancer , breast cancer
Invasive lobular carcinoma (ILC) has a different treatment response from invasive ductal carcinoma (IDC). We assessed whether perioperative chemotherapy was associated with improved prognosis in patients with ILC. Retrospective data of women who underwent surgery for ILC were extracted from the SEER database. Subjects were divided into non‐chemotherapy and chemotherapy groups. Overall, 10 537 patients were included, and 2107 patients were stratified into each group after propensity score matching. Perioperative chemotherapy significantly improved 10‐year survival rates for ILC, particularly in patients with large tumor size and lymph node metastases. Perioperative chemotherapy is effective for ILC patients with proper selection.