Open AccessIdiopathic granulomatous mastitis: Looking for the most effective therapy with the least side effects according to the severity of the disease in 374 patients in Iran
Author(s) -
Kaviani Ahmad,
Vasigh Mahtab,
Omranipour Ramesh,
Mahmoudzadeh Habibollah,
Elahi Ahmad,
Farivar Leila,
Zand Sanaz
Publication year - 2019
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/tbj.13300
Subject(s) - medicine , prednisolone , granulomatous mastitis , therapeutic modalities , disease , surgery , treatment modality , mastitis , dermatology , cure rate , pathology
The goal of this study is to compare the response rate and the recurrence rate of available therapeutic modalities in the treatment of Idiopathic Granulomatous Mastitis (IGM). 374 patients with pathologically confirmed IGM, were included. They were subdivided into three levels of severity. Close observation had the best response rate with the lowest recurrence rate in mild to moderate cases. Severe cases were mostly treated by prednisolone or underwent surgery. The outcome of prednisolone use in severe cases was comparable to NSAIDs. Overall 9% were resistant to treatment and surgical intervention is still an option among them.