Open AccessAdjuvant treatment and survival in older women with triple negative breast cancer: A Surveillance, Epidemiology, and End Results analysis
Author(s) -
Kozak Margaret M.,
Xiang Michael,
Pollom Erqi L.,
Horst Kathleen C.
Publication year - 2019
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/tbj.13251
Subject(s) - medicine , breast cancer , oncology , adjuvant , triple negative breast cancer , epidemiology , surveillance, epidemiology, and end results , incidence (geometry) , cancer , cumulative incidence , cancer registry , cohort , physics , optics
Patients with triple negative breast cancer were identified using the Surveillance, Epidemiology, and End Results database. Competing risks analysis was used to assess the cumulative incidence of breast cancer‐specific mortality (BCSM). Multivariable Fine‐Gray regression was used to identify predictors of BCSM. Women age 70+ (n = 4221) were less likely to receive chemotherapy and radiation treatment ( P < 0.0001) and had higher BCSM compared to younger women ( P < 0.0001). There were no differences in BCSM in patients who received adjuvant treatment ( P = 0.10). Stage II patients derived the greatest relative and absolute benefit from adjuvant treatment. Age was not a significant predictor of BCSM.