Open AccessAccelerated partial breast irradiation: Current status with a focus on clinical practice
Author(s) -
Miranda Fabiana A.,
Teixeira Lorine A. B.,
Heinzen Rebeca N.,
de Andrade Felipe Eduardo M.,
Hijal Tarek,
Buchholz Thomas A.,
Moraes Fabio Y.,
Poortmans Philip,
Marta Gustavo N.
Publication year - 2019
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/tbj.13164
Subject(s) - medicine , breast cancer , radiation therapy , clinical trial , randomized controlled trial , medical physics , oncology , radiology , stage (stratigraphy) , clinical practice , nuclear medicine , cancer , physical therapy , paleontology , biology
Abstract Accelerated partial breast irradiation (APBI), a radiation technique in which only the tumor bed is treated, has now become an acceptable radiation modality for selected early‐stage breast cancer patients. Compared to conventional whole breast irradiation (WBI), APBI has some benefits with regard to the reduced total irradiated breast volume and the shorter treatment time. The role of APBI, which can be delivered using diverse techniques, has been evaluated in several prospective randomized phase III trials. These clinical trials demonstrate diverging outcomes relating to local recurrence, while establishing comparable effect in terms of survival between APBI with WBI. The aim of this study was to review the current status of APBI with a focus on clinical practice.