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Tonic Pupil, a Paraneoplastic Neuro‐Ophtalmological Disease Associated with Occult Breast Cancer
Author(s) -
Peyman Alireza,
Kabiri Majid,
Peyman Mohammadreza
Publication year - 2015
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/tbj.12451
Subject(s) - medicine , photophobia , occult , blurred vision , breast cancer , pupil , radiology , cancer , ophthalmology , pathology , neuroscience , alternative medicine , biology
Here, we present a case of tonic pupil associated with occult breast cancer as a paraneoplastic neuro‐ophthalmology syndrome. A 45‐year‐old woman developed progressive photophobia and blurred vision due to unilateral Adie's tonic pupil. Magnetic resonance image of her brain and neurological examination (including deep tendon reflexes) were normal at first visit. Follow‐up examinations performed by ophthalmologist every 6 month without any change in her condition. After 2 years, patient discovered a mass in her breast which identified to be malignant after diagnostic procedures. Despite surgical and medical treatment for cancer, no change in the ocular condition was happened.

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