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Bovine kobuvirus—A comprehensive review
Author(s) -
Hao Lili,
Chen Chaoxi,
Bailey Keith,
Wang Leyi
Publication year - 2021
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.13909
Subject(s) - picornavirus , virology , biology , pathogenicity , virus , microbiology and biotechnology , rna , genetics , gene
Bovine kobuvirus (BKV) is a single‐stranded, positive sense, non‐enveloped RNA virus in genus Kobuvirus of family Picornavirus . BKV was first identified in the culture media of HeLa cell containing calf serum in 2003. Since then, BKV has been detected in 13 countries of four different continents, suggesting widespread in the world. Herein, we review the detection and genomic characterization of BKV in 13 countries. All studies tested bovine faecal samples for BKV. These studies provide evidence that BKV might be a causative agent for neonatal calf diarrhoea. Therefore, further efforts including animal challenge study are urgently needed to unveil the pathogenicity of BKV.