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The retrospective identification and molecular epidemiology of porcine circovirus type 3 ( PCV 3) in swine in Thailand from 2006 to 2017
Author(s) -
Sukmak Manakorn,
Thanantong Narut,
Poolperm Pariwat,
Boonsoongnern Alongkot,
Ratanavanichrojn Nattavut,
Jirawattanapong Pichai,
Woonwong Yonlayong,
Soda Nantana,
Kaminsonsakul Tanyanant,
Phuttapatimok Sahathat,
Wajjwalku Worawidh
Publication year - 2019
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.13057
Subject(s) - porcine circovirus , capsid , virology , circovirus , biology , phylogenetic tree , molecular epidemiology , epidemiology , virus , gene , genotype , genetics , medicine , pathology
Porcine circovirus type 3 ( PCV 3) has recently been detected in pigs worldwide, with similar clinical manifestations to porcine circovirus‐associated disease ( PCVAD ) from porcine circovirus type 2 ( PCV 2) infection. Here, we report the identification and molecular epidemiology of PCV 3 in swine in Thailand from clinical samples retrieved from 2006 to 2017. The epidemiological data revealed co‐infection with PCV 2, PRRSV , and PCV 2/ PRRSV was common in our samples. Circulating PCV 3 from this study shared a high similarity of nucleotide and deduced amino acid sequences of the partial capsid gene (96.7%–100% and 96.7%–100% respectively), indicated the genetic stability of PCV 3 in Thailand. Phylogenetic analysis based on the capsid gene revealed scatter clustering with current PCV 3 having no relation to the geographical origin of the virus strains. In this retrospective study, results have demonstrated that PCV 3 has spread extensively within Thai swine from as early as 2006 and may also be involved in PRDC and PCVAD .