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The detection of porcine circovirus 3 in Guangxi, China
Author(s) -
Wen S.,
Sun W.,
Li Z.,
Zhuang X.,
Zhao G.,
Xie C.,
Zheng M.,
Jing J.,
Xiao P.,
Wang M.,
Han J.,
Ren J.,
Liu H.,
Lu H.,
Jin N.
Publication year - 2018
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.12754
Subject(s) - porcine circovirus , circovirus , virology , china , biology , geography , virus , archaeology
Summary Porcine circovirus type 3 ( PCV 3) is a novel circovirus that was firstly detected in the USA . PCV 3 is associated with porcine dermatitis and nephropathy syndrome ( PDNS ), reproductive failure and cardiac and multisystemic inflammation. Latterly, PCV 3 was detected in Guangxi, China. Forty‐one of 108 (37.96%) samples and nine of 47 (19.14%) samples were PCV 3 positive in pig farms and pig slaughter houses, respectively. Three PCV 3 strains were sequenced and designated PCV 3‐China/ GX 2016‐1, PCV 3‐China/ GX 2016‐2 and PCV 3‐China/ GX 2016‐3. The complete genome of PCV 3‐China/ GX 2016‐2 and PCV 3‐China/ GX 2016‐3 is both 2,000 bp in length, while PCV 3‐China/ GX 2016‐1 is of 1,999 bp and has a G deletion at position of 1,155 in its genome. The complete genome and capsid nucleotide of the three PCV 3 strains identified in this study shared 97.5%–99.4% and 96.7%–99.1% identities with that of the other PCV 3 strains available in NCBI , respectively. Phylogenetic analysis based on complete genome and capsid gene of 35 PCV 3 strains showed that the three PCV 3 sequences from Guangxi Province were divided into two clusters. The results of this study contribute to the understanding of PCV 3 molecular epidemiology.