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Full‐Genome Sequence of Porcine Circovirus type 3 recovered from serum of sows with stillbirths in Brazil
Author(s) -
Tochetto C.,
Lima D. A.,
Varela A. P. M.,
Loiko M. R.,
Paim W. P.,
Scheffer C. M.,
Herpich J. I.,
Cerva C.,
Schmitd C.,
Cibulski S. P.,
Santos A. C.,
Mayer F. Q.,
Roehe P. M.
Publication year - 2018
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.12735
Subject(s) - porcine circovirus , biology , orfs , genome , genetics , genbank , circovirus , virology , open reading frame , gene , virus , peptide sequence
Summary Two full‐genome sequences of porcine circovirus type 3 ( PCV 3) are reported. The genomes were recovered from pooled serum samples from sows who had just delivered litters with variable numbers of stillbirths. The two circular genomes ( PCV 3‐ BR / RS /6 and PCV 3‐ BR / RS /8) are 2,000 nucleotides long and contain two open reading frames (ORFs) oriented in opposite directions that encode the putative capsid (Cap) and replicase (Rep) proteins. The intergenic region contains a stem‐loop motif, as reported for other circoviruses. Rolling circle replication motifs and putative helicase domains were identified in the Rep coding region. The degree of overall nucleotide similarity between the genomes reported here and those available at GenBank was higher than 97%. No PCV 3 sequence was detected in pooled serum samples from sows which had no stillbirths on the same farms. However, further studies are necessary to confirm the association between PCV 3 and the occurrence of stillbirths.