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Gaps in African swine fever: Analysis and priorities
Author(s) -
Arias M.,
Jurado C.,
Gallardo C.,
FernándezPinero J.,
SánchezVizcaíno J. M.
Publication year - 2018
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.12695
Subject(s) - epidemiology , african swine fever , african swine fever virus , molecular epidemiology , herd , virology , environmental health , biology , medicine , veterinary medicine , virus , pathology , biochemistry , gene , genotype
Summary African swine fever ( ASF ) causes greater sanitary, social and economic impacts on swine herds than many other swine diseases. Although ASF was first described in 1921 and it has affected more than fifty countries in Africa, Europe and South America, several key issues about its pathogenesis, immune evasion and epidemiology remain uncertain. This article reviews the main characteristics of the causative virus, its molecular epidemiology, natural hosts, clinical features, epidemiology and control worldwide. It also identifies and prioritizes gaps in ASF from a horizontal point of view encompassing fields including molecular biology, epidemiology, prevention, diagnosis and vaccine development. The purpose of this review is to promote ASF research and enhance its control.