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Fatal peste des petits ruminants disease in Chowsingha
Author(s) -
Jaisree S.,
Aravindhbabu R. P.,
Roy P.,
Jayathangaraj M. G.
Publication year - 2018
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.12694
Subject(s) - biology , peste des petits ruminants , subfamily , virus , gene , peste des petits ruminants virus , virology , 18s ribosomal rna , lineage (genetic) , ribosomal rna , genetics
Summary This communication reports fatal Peste des petits ruminants (PPR) disease in Chowsingha ( Tetracerus quadricornis), a member of the subfamily Bovinae and family Bovidae captured in a Zoological Park. The animals showed clinical signs of acute respiratory disease with frothy nasal discharge (1–2 days) and mortality of twenty animals (80%) within 48 hr. Necropsy of dead Chowsingha showed haemorrhagic patches in trachea and severe congestion of lungs and ocular mucosa. There was no characteristic lesion in the intestine. Swabs from trachea and nasal tract along with tissue samples of spleen and lung from dead animals were found positive for PPR virus based on reverse transcription–polymerase chain reaction using H gene and partial N gene‐specific primers. Sequence analysis of complete H gene and partial N gene confirmed the aetiological agent as PPR virus lineage IV. The identity of the Chowsingha tissues used for PPRV isolation was confirmed by the 12S ribosomal RNA gene sequencing, and the amplified gene was analysed identically to the Chowsingha mitochondrial 12S ribosomal RNA gene. The present information of PPR in Chowsingha is the first report of PPRV lineage IV causing cross‐species fatal disease in subfamily bovinae and family Bovidae. The acute manifestation of the disease indicates high susceptibility of this vulnerable wild bovid species to PPR lineage IV. This report extends host range and demands enhanced surveillance among subfamily bovinae to strengthen PPR eradication programme.