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Identification of a New Genotype of African Swine Fever Virus in Domestic Pigs from Ethiopia
Author(s) -
Achenbach J. E.,
Gallardo C.,
NietoPelegrín E.,
RiveraArroyo B.,
DegefaNegi T.,
Arias M.,
Jenberie S.,
Mulisa D. D.,
Gizaw D.,
Gelaye E.,
Chibssa T. R.,
Belaye A.,
Loitsch A.,
Forsa M.,
Yami M.,
Diallo A.,
Soler A.,
Lamien C. E.,
SánchezVizcaíno J. M.
Publication year - 2017
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.12511
Subject(s) - african swine fever virus , genotype , outbreak , biology , virology , gene , virus , african swine fever , sequence analysis , veterinary medicine , genetics , medicine
Summary African swine fever ( ASF ) is an important emerging transboundary animal disease ( TAD ), which currently has an impact on many countries in Africa, Eastern Europe, the Caucasus and the Russian Federation. The current situation in Europe shows the ability of the virus to rapidly spread, which stands to threaten the global swine industry. At present, there is no viable vaccine to minimize spread of the disease and stamping out is the main source of control. In February 2011, Ethiopia had reported its first suspected outbreaks of ASF . Genomic analyses of the collected ASF virus ( ASFV ) strains were undertaken using 23 tissue samples collected from domestic swine in Ethiopia from 2011 to 2014. The analysis of Ethiopian ASFV s partial p72 gene sequence showed the identification of a new genotype, genotype XXIII , that shares a common ancestor with genotypes IX and X, which comprise isolates circulating in Eastern African countries and the Republic of Congo. Analysis of the p54 gene also followed the p72 pattern and the deduced amino acid sequence of the central variable region ( CVR ) of the B602L gene showed novel tetramer repeats not previously characterized.