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Review: Capripoxvirus Diseases: Current Status and Opportunities for Control
Author(s) -
Tuppurainen E. S. M.,
Venter E. H.,
Shisler J. L.,
Gari G.,
Mekonnen G. A.,
Juleff N.,
Lyons N. A.,
De Clercq K.,
Upton C.,
Bowden T. R.,
Babiuk S.,
Babiuk L. A.
Publication year - 2017
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.12444
Subject(s) - outbreak , transmission (telecommunications) , safer , disease , biology , veterinary medicine , virology , environmental health , medicine , computer security , pathology , computer science , electrical engineering , engineering
Summary Lumpy skin disease, sheeppox and goatpox are high‐impact diseases of domestic ruminants with a devastating effect on cattle, sheep and goat farming industries in endemic regions. In this article, we review the current geographical distribution, economic impact of an outbreak, epidemiology, transmission and immunity of capripoxvirus. The special focus of the article is to scrutinize the use of currently available vaccines to investigate the resource needs and challenges that will have to be overcome to improve disease control and eradication, and progress on the development of safer and more effective vaccines. In addition, field evaluation of the efficacy of the vaccines and the genomic database available for poxviruses are discussed.