The distribution of  HLA‐DRB3  alleles among  HLA‐DRB1*03:01 ‐positive haplotypes | Zendy

Stingl Jankovic K. | Zendy; Grubic Z. | Zendy; Jakupic J. | Zendy; Burek Kamenaric M. | Zendy; Maskalan M. | Zendy; Zunec R. | Zendy

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The distribution of HLA‐DRB3 alleles among HLA‐DRB1*03:01 ‐positive haplotypes

Author(s) -

Stingl Jankovic K.,

Grubic Z.,

Jakupic J.,

Burek Kamenaric M.,

Maskalan M.,

Zunec R.

Publication year - 2018

Publication title -

hla

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.347

H-Index - 99

eISSN - 2059-2310

pISSN - 2059-2302

DOI - 10.1111/tan.13328

Subject(s) - allele , haplotype , human leukocyte antigen , genetics , biology , polymorphism (computer science) , hla a , immunology , gene , antigen

HLA‐DRB3 allelic polymorphism on HLA‐DRB1*03:01 ‐positive haplotypes was investigated among 104 cadaveric donors typed for HLA‐A, ‐B, ‐DRB1, and ‐DRB3. Only HLA‐DRB3*01:01:02 and ‐DRB3*02:02:01:01 alleles were detected among HLA‐DRB1*03:01‐ positive individuals and their distribution depended on HLA‐B*08 presence: nearly all HLA‐B*08 ‐positive samples carried DRB3*01:01:02 , while HLA‐DRB3*02:02:01:01 was more frequent among HLA‐B*08 ‐negative subjects.

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