Open AccessEvaluation of the efficacy of triamcinolone acetonide in the treatment of keloids by high‐frequency ultrasound
Author(s) -
Cai Lei,
Hu Murong,
Lin Lele,
Zheng Tianyin,
Liu Jingjing,
Li Zhiming
Publication year - 2020
Publication title -
skin research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.521
H-Index - 69
eISSN - 1600-0846
pISSN - 0909-752X
DOI - 10.1111/srt.12820
Subject(s) - triamcinolone acetonide , medicine , keloid , ultrasound , acetonide , surgery , dermatology , radiology
Background Intralesional injection of triamcinolone acetonide is an effective method for treating keloids. It still lacks effective and objective evaluation methods. This study aimed to observe the efficacy of intralesional triamcinolone acetonide injections for the treatment of keloids and to explore the role of high‐frequency ultrasound in the monitoring and evaluation of keloids therapy. Methods Fifty‐one patients with keloids were treated with triamcinolone acetonide, once a week for 4 weeks. Lesions were detected, recorded, and evaluated using digital photography and high‐frequency ultrasound before and after treatment. Results High‐frequency ultrasound showed the depth of drug injection. After the last treatment, an average decrease in dermal tissue layer thickness of 39.0% is compared with before treatment. In addition, there are significant differences in the effectiveness of clinical assessments and ultrasound assessments of keloids with or without subjective symptoms. Conclusion The observed results confirmed that intralesional injections of triamcinolone acetonide can effectively treat keloids. High‐frequency ultrasound can be used as a therapeutic monitoring and therapeutic evaluation tool for intralesional injections of triamcinolone acetonide.