Open AccessValidation of GPS kin Barrier ® for assessing epidermal permeability barrier function and stratum corneum hydration in humans
Author(s) -
Ye L.,
Wang Z.,
Li Z.,
Lv C.,
Man M.Q.
Publication year - 2019
Publication title -
skin research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.521
H-Index - 69
eISSN - 1600-0846
pISSN - 0909-752X
DOI - 10.1111/srt.12590
Subject(s) - transepidermal water loss , stratum corneum , barrier function , skin barrier , chemistry , permeability (electromagnetism) , biophysics , dermatology , medicine , pathology , biology , biochemistry , microbiology and biotechnology , membrane
Background Measurements of transepidermal water loss ( TEWL ) and stratum corneum ( SC ) hydration are important for assessing epidermal functions. However, the availability of reliable and user‐friendly devices, which can simultaneously measure both TEWL and SC hydration and can allow health providers to remotely access data in time, is limited. Materials and Methods GPS kin Barrier ® was compared with MPA 5 system in the measurements of TEWL and SC hydration on the cheek, the dorsal hand, and the forearm in 200 normal volunteers, including 126 females and 74 males, aged 1‐78 years with an average age of 45.24 ± 1.04 years. Correlation of data measured with MPA 5 system and GPS kin Barrier ® was determined. Results Levels of both TEWL and SC hydration measured with the Barrie GPS kin Barrier ® were lower than that with MPA 5 system on all 3 body sites except for hydration on the cheek. The levels of both TEWL and SC hydration measured with GpSkin Barrier ® were correlated well with that measured with MPA 5 system on all 3 body sites Conclusions GPS kin Barrier ® is a reliable, affordable, and versatile device for assessing epidermal permeability barrier function and SC hydration.