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One year of Football Fitness improves L1–L4 BMD, postural balance, and muscle strength in women treated for breast cancer
Author(s) -
Uth Jacob,
Fristrup Bjørn,
Sørensen Victor,
Helge Eva Wulff,
Christensen Maja Kjærgaard,
Kjærgaard Julie Boye,
Møller Trine Kjeldgaard,
Helge Jørn Wulff,
Jørgensen Niklas Rye,
Rørth Mikael,
Vadstrup Eva Soelberg,
Krustrup Peter
Publication year - 2021
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/sms.13963
Subject(s) - medicine , bone mineral , n terminal telopeptide , lean body mass , balance (ability) , physical therapy , breast cancer , osteoporosis , osteocalcin , cancer , body weight , biology , biochemistry , alkaline phosphatase , enzyme
Purpose To examine efficacy of 12 months Football Fitness offered twice per week on bone mineral density (BMD), bone turnover markers (BTM), postural balance, muscle strength, and body composition in women treated for early‐stage breast cancer (BC). Methods Women treated for early‐stage BC were randomized to Football Fitness (FFG, n = 46) or control (CON, n = 22) in a 2:1 ratio for 12 months, with assessments performed at baseline, 6 months and 12 months. Outcomes were total body‐, lumbar spine‐ and proximal femur BMD, total body lean and fat mass, leg muscle strength, postural balance, and plasma amino‐terminal propeptide of type 1 procollagen (P1NP), osteocalcin, and C‐terminal telopeptide of type 1 collagen (CTX). Intention‐to‐treat (ITT) analyses and per‐protocol analyses (≥50% attendance in FFG) were performed using linear mixed models. Results Participants in FFG completing the 12‐month intervention ( n = 33) attended 0.8 (SD = 0.4) sessions per week. Intention to treat analysis of mean changes over 12 months showed significant differences ( p <.05) in L1–L4 BMD (0.029 g/cm 2 , 95%CI: 0.001 to 0.057), leg press strength (7.2 kg, 95%CI: 0.1 to 14.3), and postural balance (−4.3 n need of support, 95%CI: −8.0 to −0.7) favoring FFG compared to CON. In the per‐protocol analyses, L1–L4 and trochanter major BMD were improved ( p = .012 and .030, respectively) in FFG compared with CON. No differences were observed between groups in BTMs in the ITT or per protocol analyses. Conclusion One year of Football Fitness training may improve L1–L4 BMD, leg muscle strength, and postural balance in women treated for early‐stage breast cancer.