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Effects of acute and 2‐week administration of oral salbutamol on exercise performance and muscle strength in athletes
Author(s) -
Hostrup M.,
Kalsen A.,
Auchenberg M.,
Bangsbo J.,
Backer V.
Publication year - 2016
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/sms.12298
Subject(s) - salbutamol , medicine , placebo , sprint , isometric exercise , athletes , physical therapy , wingate test , anesthesia , oral administration , anaerobic exercise , asthma , alternative medicine , pathology
Our objective was to investigate effects of acute and 2‐week administration of oral salbutamol on repeated sprint ability, exercise performance, and muscle strength in elite endurance athletes. Twenty male elite athletes [ VO 2max : 69.4 ± 1.8 (Mean ± SE ) mL/min/kg], aged 25.9 ± 1.4 years, were included in a randomized, double‐blinded and placebo‐controlled parallel study. At baseline, after acute administration, and again after 2‐week administration of the study drugs (8 mg salbutamol or placebo), subjects' maximal voluntary contraction ( MVC ) of m. quadriceps and isometric endurance of m. deltoideus were measured, followed by three repeated W ingate tests. Exercise performance at 110% of VO 2max was determined on a bike ergometer. Acute administration of salbutamol increased peak power during first W ingate test by 4.1 ± 1.7% ( P < 0.05). Two‐week administration of salbutamol increased ( P < 0.05) peak power during first and second W ingate test by 6.4 ± 2.0 and 4.2 ± 1.0%. Neither acute nor 2‐week administration of salbutamol had any effect on MVC , exercise performance at 110% of VO 2max or on isometric endurance. No differences were observed in the placebo group. In conclusion, salbutamol benefits athletes' sprint ability. Thus, the present study supports the restriction of oral salbutamol in competitive sports.