Premium
Assessment of magnetic resonance techniques to measure muscle damage 24 h after eccentric exercise
Author(s) -
Fulford J.,
Eston R. G.,
Rowlands A. V.,
Davies R. C.
Publication year - 2015
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/sms.12234
Subject(s) - vastus medialis , phosphocreatine , magnetic resonance imaging , eccentric , medicine , eccentric exercise , rectus femoris muscle , skeletal muscle , effective diffusion coefficient , nuclear magnetic resonance , anatomy , chemistry , nuclear medicine , muscle damage , electromyography , physical medicine and rehabilitation , radiology , physics , quantum mechanics , energy metabolism
The study examined which of a number of different magnetic resonance ( MR ) methods were sensitive to detecting muscle damage induced by eccentric exercise. Seventeen healthy, physically active participants, with muscle damage confirmed by non‐ MR methods were tested 24 h after performing eccentric exercise. Techniques investigated whether damage could be detected within the quadriceps muscle as a whole, and individually within the rectus femoris, vastus lateralis ( VL ), vastus medialis ( VM ), and vastus intermedius ( VI ). Relative to baseline values, significant changes were seen in leg and muscle cross‐sectional areas and volumes and the resting inorganic phosphate concentration. Significant time effects over all muscles were also seen in the transverse relaxation time ( T 2) and apparent diffusion coefficient ( ADC ) values, with individually significant changes seen in the VL , VM , and VI for T 2 and in the VI for ADC . A significant correlation was found between muscle volume and the average T 2 change ( r = 0.59) but not between T 2 and ADC or P i alterations. There were no significant time effects over all muscles for magnetization transfer contrast images, for baseline pH , phosphocreatine ( PC r), phosphodiester, or ATP metabolite concentrations or the time constant describing the rate of PC r recovery following exercise.