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Relationship between aerobic endurance training and dynamic cerebral blood flow regulation in humans
Author(s) -
Ichikawa D.,
Miyazawa T.,
Horiuchi M.,
Kitama T.,
Fisher J. P.,
Ogoh S.
Publication year - 2013
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/sms.12082
Subject(s) - cerebral blood flow , aerobic exercise , medicine , physical medicine and rehabilitation , endurance training , training (meteorology) , blood flow , physical therapy , cardiology , physics , meteorology
The incidence of orthostatic intolerance is elevated in endurance‐trained individuals. We sought to test the hypothesis that aerobic endurance training is associated with an attenuated control of the cerebral vasculature. Endurance trained ( ET , n = 13) and age‐matched untrained ( UT , n = 11) individuals (peak O 2 consumption, mean ± SEM ; 63 ± 1 vs 42 ± 1 mL /min/kg, P < 0.05) were examined while supine and seated upright. Dynamic cerebral autoregulation ( CA ) was assessed by calculation of the rate of regulation ( RoR ) from the arterial blood pressure ( ABP ) and middle cerebral artery ( MCA ) mean blood velocity ( V mean ) responses to a bilateral thigh cuff release, which evoked a transient hypotension. Cerebral oxygenation (oxyhemoglobin; HbO 2 ) was determined with near‐infrared spectroscopy. When seated upright, cuff release evoked a greater decrease in ABP ( P < 0.001), MCA V mean ( P = 0.096) and HbO 2 ( P < 0.001) in ET compared with UT . However, RoR was similar in ET and UT individuals while seated upright (to 0.193 ± 0.039 vs 0.129 ± 0.029/s, P > 0.05), and there was no significant difference in the relative change in RoR from the supine to upright positions (Δ RoR : −65 ± 7 and −69 ± 7%, for ET and UT , respectively). These findings suggest that aerobic endurance training is not associated with an attenuation in dynamic CA .