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Principles of cross‐network communication in human resting state fMRI
Author(s) -
Mitra Anish,
Raichle Marcus E.
Publication year - 2018
Publication title -
scandinavian journal of psychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.743
H-Index - 72
eISSN - 1467-9450
pISSN - 0036-5564
DOI - 10.1111/sjop.12422
Subject(s) - retrosplenial cortex , default mode network , task positive network , neuroscience , psychology , resting state fmri , prefrontal cortex , human brain , functional magnetic resonance imaging , nerve net , frontal eye fields , functional connectivity , posterior parietal cortex , cortex (anatomy) , cognition , eye movement , saccade
Directed signaling among and within the large‐scale networks of the human brain is functionally critical. Recent advances in our understanding of spontaneous fluctuations of the fMRI BOLD signal have provided strategies to study the spatial‐temporal properties of directed signaling at infra‐slow frequencies. Herein we explore the relationship between two canonical systems of the human brain, the default mode network ( DMN ) and the dorsal attention network ( DAN ) whose anti‐correlated relationship is well known but poorly understood. We find that within the DMN , activity moves from retrosplenial to prefrontal cortex whereas in the DAN activity moves from the frontal eye fields to the parietal cortex. Bi‐directional communication between the two networks occurs via their earliest elements (i.e., from the retrosplenial cortex of the DMN to the frontal eye fields of the DAN ). This framework for network communication appears to generalize across all networks providing an expanded basis for understanding human brain function.