Premium
Physiology and pathology of eosinophils: Recent developments
Author(s) -
Renz Harald,
Bachert Claus,
Berek Claudia,
Hamelmann Eckard,
LeviSchaffer Francesca,
Raap Ulrike,
Simon HansUwe,
Ploetz Sabine,
Taube Christian,
Valent Peter,
Voehringer David,
Werfel Thomas,
Zhang Nan,
Ring Johannes
Publication year - 2021
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/sji.13032
Subject(s) - eosinophilic , disease , german , medicine , immunology , eosinophil , eosinophilic gastroenteritis , pathology , history , asthma , archaeology
Over the last century, eosinophils have been regarded ambiguously either as ‘friends’ or ‘foes’. Recent developments have greatly enhanced our understanding of the role and function of eosinophils in health and disease. Pathogenic eosinophilic inflammation can lead to severe diseases in various organs, such as the gastrointestinal tract, airways, heart and skin. In a 2‐day focus workshop of the German Society for Allergology and Clinical Immunology (DGAKI), the state of the art was discussed and practical recommendations for diagnosis and treatment of eosinophilic diseases, with a particular focus on new biologics, such as anti‐interleukin 5 and anti‐interleukin 5R, were derived.