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Body composition and ventricular function in hemodialysis patients
Author(s) -
Carbayo Javier,
Abad Soraya,
Verde Eduardo,
Muñoz de Morales Alejandra,
GonzalezRojas Angela,
Acosta Adriana,
Mijaylova Antonia,
Bascuñana Arturo,
Vega Almudena,
Goicoechea Marian
Publication year - 2021
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/sdi.12955
Subject(s) - medicine , ejection fraction , cardiology , ventricular function , hemodialysis , dialysis , population , heart failure , environmental health
There is no evidence about the potential role of body composition on cardiovascular mortality in dialysis patients. The aim of this study was to assess the relationship between body composition and changes in ventricular function. We conducted an observational study over a population of 78 patients on chronic hemodialysis. A transthoracic echocardiogram and a bioimpedance were performed at the beginning and at the end of the study. The mean follow‐up time was 30.6 months. Patients who had a higher fat tissue index (FTI > 9.20 kg/m 2 ) experienced a worsening in right and left ventricular function. They developed a greater fall in tricuspid annular plane systolic excursion (TAPSE) (−1 ± 4.3 mm) and left ventricular ejection fraction (LVEF)(−4.2 ± 6.8%), compared to those with lower FTI ( p = 0.032 and p = 0.045, respectively). No associations were found between any other echocardiography or body composition parameters and overall mortality. Patients with right ventricular dysfunction (determined as TAPSE) experienced a tendency to higher mortality rate along the study (HR for mortality of 13.5 (95% CI, 1.1–166.7; p = 0.041)]. A higher fat tissue index could be associated with a deleterious effect over right and left ventricular function in dialysis patients.