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Vaccination practices in dialysis patients: A narrative review
Author(s) -
Kosmadakis Georges,
Albaret Julie,
Correia Enrique Da Costa,
Somda Frederic,
Aguilera Didier
Publication year - 2018
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/sdi.12709
Subject(s) - medicine , vaccination , narrative review , intensive care medicine , dialysis , immunology
In a period of turmoil concerning vaccination practices, there is a serious conflict between scientifically reasonable, evidence‐based guidelines and the far‐fetched rumors or misconceptions concerning the vaccination practices in the general population. When a significant portion of the medical and paramedical personnel may be deliberately unvaccinated against common biological agents, achieving effective vaccination rates in the dialysis population may be complicated. Vaccination rates are unacceptably low in dialysis patients and seroconversion rates are even lower; further, serological follow‐up is generally poor. The particularly anergic immune system of the advanced chronic kidney disease patients is partly a cause of both high rates of infection and low rates of seroconversions. This narrative review is an effort to summarize current knowledge concerning the vaccination practices in dialysis patients with some specific recommendations based on these facts. Of particular interest is a new vaccine, the Zoster Recombinant, Adjuvanted Vaccine (Shingrix), which we will include in our discussion.